Brain Aggregate Cell Cultures – Neurotoxicity

A nervous system that has an intricate anatomy and unique structural and functional characteristics has a highly complex organization, containing multiple types of cells with multiple functions.

In vitro neurotoxicity models are used in order to gain a better understanding and help with safety issues that can be addressed earlier in the drug development process.

In vitro neurotoxicity assays provided by DA-TA Biotech are used to study chemicals’ effects on neuromorphology and electrophysiology.

We can evaluate neurotoxicity by analyzing the effect of compounds on cell viability, apoptosis, membrane integrity, oxidative stress, and mitochondrial dysfunction.

Compared to animal tests, in vitro cell-based tests are much cheaper and faster, and at the same time, they provide more information about the mechanisms involved, so they are more appropriate for early screening.

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