da-ta-biotech l.t.d

ß-Site for R&D

da-ta-biotech l.t.d

ß-Site for R&D

Our services

Microbiology

Da-Ta Biotech provides Research and Development (R&D) bacteriology service  where bacteria and Phages serve both as  tools for research, included in validates models, and being investigated for improving drugs mechanism of action
Biosafety level 1 – bacterial assays – phage assays – bacterial banking – phage banking – antibacterial activity assays -
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RNA and DNA technologies at our customers’ service are fast and effective in order to advance any genetic engineering, cloning or expression assays
PCR – real time PCR – Reverse Transcription – primers / probes construction – cloning – RNA/DNA extraction - Plasmids
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Biochemistry

Cell biology is our Workspace. Drug mode of action (MOA), drug safety and druggability of a compound are directly effecting and effected from this “working environment”. The effect of proteins expression and activity is a main key for pharmaceuticals development.
Western blot – ELISA – ImmunoHistochemistry (IHC) – Protein biding assays – Enzyme kinetics – Protein interaction – KITS – Detection: colorimetric, fluorometric and luminometric.
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Franz cells

Da-Ta Biotech’s state of the art sophisticated Hamilton Vertical diffusion device enables Israeli drug developing companies in sorting formulations for topical treatments.
Permeation assays - Artificial membrane – pig skin/ human skin – gel, liquid, ointment formulations.
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Tissue culture

Da-Ta Biotech extracts, propagates and prepares cell banks of cells from a wide range of sources including ATCC or any global source center, viable tissue collected within animal studies, viable tissue collected from a clinical study for R&D.
Biosafety level 2 - Cell banking –– cell lines – cancer cells – primary cell extraction - primary cells propagation – cell immortalization - Transient and stable transfections.
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Biocompatibility

Biocompatibility of a medical device is tested according to ISO 10993-5:2009. Being an Israeli CRO for biological assays is providing direct access for our clients for screening different prototypes, preparations or processes before advancing abroad to a GLP certified provider such as NAMSA.
- cytotoxicity assays (ISO 10993-5:2009) – cell viability – Medical Device testing – ADME Tox – Biological samples evaluation.
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Employing a validated in vitro model as well as setting up a new cell based research tool based on our customers’ needs, are both accomplished shortly and effectively by collaborations all over the pharmaceutical industry and suppliers.
Biosafety level 2 - Cell proliferation – apoptosis - cytotoxicity assays (ISO 10993-5:2009) – cell viability – metabolic assays - Cell Adhesion and attachment Cell migration – cytokines assays - Transient and stable transfections - Induction of cell differentiation.
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Virology

Our researchers are well practiced and certified for researching viruses BSL2. Adeno viruses and Lentiviruses are used for Pharmaceutical developments such as CAR-T and Immortalization.
Biosafety level 2 – cell infection – cytopathic effects – lenti viral plateform – adenoviral tools.
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Our feature

Da-Ta Biotech provides both the scientific guidance and the hand on bench work for harnessing these tools for our customers research benefit and success

Cancer & In vitro models

Dermatology
Immune response
Allergy
Inflamation
Angiogenesis
Citotoxicity
Metabolic disorders

Platforms

Sheep EF plasma
Phage display
Vector engineering
Retro/LV production
Gene ecpression
Franz cells
Citotoxicity ISO 10993-5:2009

Tissue Culture Banking

Cells
Viruses
Phages
Bacteria

Pre clinical consulting:

Mile stones setup
Project characterization
Scientific Due diligence
Helsinki submission
Ethical committee requests
Scientific writing

Our customers

Governmental Research Institutes

Government research and IDF (Israeli Army)

Academy

Universities and Research institutes

Industry

Pharmaceutical, Biotechnology, Medical devices, Environmental

hospitals

All Israeli Medical facilities and funds

Our partners

Contact us

Adress

2 Bergman St. 3rd floor, Science Center Bldg,
Rechovot 76701, Israel
P.O.Box 4194, Rehovot 74140, Israel

Tel

Tel: +972-8-9100575
Fax: +972-8-9100574

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